PMID- 20383002
OWN - NLM
STAT- MEDLINE
DA  - 20100412
DCOM- 20100527
LR  - 20141223
IS  - 1399-0047 (Electronic)
IS  - 0907-4449 (Linking)
VI  - 66
IP  - Pt 4
DP  - 2010 Apr
TI  - Features and development of Coot.
PG  - 486-501
LID - 10.1107/S0907444910007493 [doi]
AB  - Coot is a molecular-graphics application for model building and validation of
      biological macromolecules. The program displays electron-density maps and atomic 
      models and allows model manipulations such as idealization, real-space
      refinement, manual rotation/translation, rigid-body fitting, ligand search,
      solvation, mutations, rotamers and Ramachandran idealization. Furthermore, tools 
      are provided for model validation as well as interfaces to external programs for 
      refinement, validation and graphics. The software is designed to be easy to learn
      for novice users, which is achieved by ensuring that tools for common tasks are
      'discoverable' through familiar user-interface elements (menus and toolbars) or
      by intuitive behaviour (mouse controls). Recent developments have focused on
      providing tools for expert users, with customisable key bindings, extensions and 
      an extensive scripting interface. The software is under rapid development, but
      has already achieved very widespread use within the crystallographic community.
      The current state of the software is presented, with a description of the
      facilities available and of some of the underlying methods employed.
FAU - Emsley, P
AU  - Emsley P
AD  - Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1
      3QU, England. paul.emsley@bioch.ox.ac.uk
FAU - Lohkamp, B
AU  - Lohkamp B
FAU - Scott, W G
AU  - Scott WG
FAU - Cowtan, K
AU  - Cowtan K
LA  - eng
GR  - BB/D522403/Biotechnology and Biological Sciences Research Council/United Kingdom
GR  - BB/D522403/1/Biotechnology and Biological Sciences Research Council/United
      Kingdom
GR  - BBF0202281/Biotechnology and Biological Sciences Research Council/United Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100324
PL  - England
TA  - Acta Crystallogr D Biol Crystallogr
JT  - Acta crystallographica. Section D, Biological crystallography
JID - 9305878
RN  - 0 (Proteins)
RN  - 63231-63-0 (RNA)
RN  - 9007-49-2 (DNA)
SB  - IM
MH  - Crystallography, X-Ray/*methods
MH  - DNA/analysis/chemistry
MH  - Models, Molecular
MH  - Nucleic Acid Conformation
MH  - Protein Structure, Tertiary
MH  - Proteins/analysis/chemistry
MH  - RNA/analysis/chemistry
MH  - *Software Design
PMC - PMC2852313
OID - NLM: PMC2852313
EDAT- 2010/04/13 06:00
MHDA- 2010/05/28 06:00
CRDT- 2010/04/13 06:00
PHST- 2009/06/09 [received]
PHST- 2010/02/26 [accepted]
PHST- 2010/03/24 [epublish]
AID - S0907444910007493 [pii]
AID - 10.1107/S0907444910007493 [doi]
PST - ppublish
SO  - Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501. doi:
      10.1107/S0907444910007493. Epub 2010 Mar 24.